Clinical Focus ›› 2025, Vol. 40 ›› Issue (7): 643-646.doi: 10.3969/j.issn.1004-583X.2025.07.010

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Castleman's disease of the abdomen in children: Report of two cases and literature review

Wang Doudou, Jiang Jian, Zhao Wei, Li Xuerong, Sun Lirong, Wang Lingzhen()   

  1. Department of Pediatric Hematology and Oncology, the Affiliated Hospital of Qingdao University, Qingdao 266000, China
  • Received:2025-03-20 Online:2025-07-20 Published:2025-07-17
  • Contact: Wang Lingzhen E-mail:hopewang2006@163.com

Abstract:

Objective To summarize the clinical features of Castleman 's disease of the abdomen in children, thus improving the understanding of its diagnosis, treatment and prognosis. Methods Clinical data of two children with Castleman's disease of the abdomen admitted to the Affiliated Hospital of Qingdao University were retrospectively analyzed, and the related literatures were reviewed. Results Both patients underwent surgical resection and they were in complete remission during the follow-up period. In addition, anemia improved significantly after surgical resection, and the weight also increased compared with the pre-treatment value. Conclusion Castleman's disease of the abdomen in children is rare. Complete resection of the tumor is the main treatment for patients with abdominal single-center Castleman’s dissease, and the prognosis is good.

Key words: Castleman disease, abdomen, child

CLC Number: