Advances in anticoagulant therapy after acute coronary syndrome

doi:10.3969/j.issn.1004-583X.2018.09.005

Abstract

Abstract: Vascular endothelial damage caused by erosion or rupture of coronary atherosclerotic plaque is the pathophysiological basis of thrombosis in coronary artery lesions. The onset of acute coronary syndrome(ACS) is often accompanied by changes in electrocardiogram, increased markers of myocardial injury and the appearance of symptoms of angina pectoris. Antiplatelet and anticoagulant therapy is the key to the treatment of ACS. The effective use of antiplatelet and anticoagulant drugs can reduce the occurrence of ischemic events such as myocardial infarction, thrombosis in stent and a reduction in mortality. This article reviews current evidences for anticoagulants in ACS.

Key words: acute coronary syndrome, anticoagulants, ischemic, bleeding

Rao Mingyue, Wang Yaling, Zhang Guoru, Wang Mei. Advances in anticoagulant therapy after acute coronary syndrome[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2018.09.005.

Add to citation manager EndNote|Ris|BibTeX

URL: http://www.lchc.cn/EN/10.3969/j.issn.1004-583X.2018.09.005

http://www.lchc.cn/EN/Y2018/V33/I9/761

[1]	Bu Zhiping, ZhaoYu , Liu Hongfeng, Liu Guangliang, Han Wenqin. A clinical investigation into the role of family members involved in the rehabilitation training for individuals with acute ischemic stroke [J]. Clinical Focus, 2025, 40(3): 222-226.
[2]	Yu Jingyi, Si Yuanguo, Lan Cuixia, Xing Jiaxuan. Safety and efficacy of rivaroxaban in the treatment of discharged COVID-19 patients: A meta-analysis [J]. Clinical Focus, 2024, 39(6): 485-493.
[3]	Wang Zhongqi, Li Jinzhao, Wu Nan. Correlation between systemic immune inflammation index and multivessel coronary disease in patients with acute coronary syndrome [J]. Clinical Focus, 2024, 39(6): 512-517.
[4]	Song Mengjiao, Wang Ruiqi, Cao Can, Cheng Guangsen, Liu Yu, Li Zhongliang, Yang Jianhao. Correlation between serum uric acid with TOAST classification and prognosis in patients with first-onset acute ischemic stroke [J]. Clinical Focus, 2024, 39(3): 216-221.
[5]	Xin Yanhong, Lang Guiyan, Chen Ziwei, Wang Dongyu. Value of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio in predicting cognitive impairment in patients with acute mild ischemic stroke [J]. Clinical Focus, 2023, 38(6): 504-509.
[6]	He Xiangyu, Pan Yan, Zhang Xiaolin. Correlation between serum lipoprotein-associated phospholipase A2 level and the severity and prognosis of acute ischemic stroke [J]. Clinical Focus, 2023, 38(4): 315-318.
[7]	Jia Yangjuan, Han Ning, Guo Hui, Li Yanpeng, Li Cancan, Li Jianguo. Value of Mini Mental State Examination and Montreal Cognitive Assessment in screening mild vascular cognitive impairment at post-stroke [J]. Clinical Focus, 2023, 38(3): 221-226.
[8]	Yao Meifen, Ding Gangyu, Xu Jianhua, Wang Guojiang. Efficacy and safety of recombinant tissue plasminogen activator in patients with acute mild ischemic stroke [J]. Clinical Focus, 2023, 38(3): 227-231.
[9]	Luo Weigang, Xu Yuzhu, Zhang Lingyan, Wu Xiangyun, Bu Wei, Ren Huiling. Predictive value of the platelet function PFA-200 P2Y on the secondary prevention of acute ischemic stroke with clopidogrel [J]. Clinical Focus, 2023, 38(11): 979-983.
[10]	Xu Wendeng, Shen Yi, Zhang Xiaofeng. Correlation between nonspecific ST-T abnormalities in electrocardiogram and recurrence of acute ischemic stroke [J]. Clinical Focus, 2023, 38(10): 883-886.
[11]	Ding Siqi, Liu Shihua, Zhang Chao, Zhong Ping, Cao Li. Risk factors for epilepsy after delayed post-stroke epilepsy and its clinical correlation with blood Hcy, hs-CRP and D-D [J]. Clinical Focus, 2023, 38(10): 893-897.
[12]	Ma Jinghong, Yang Qian, Jia Yongjian, Dang Yi. Risks of cardiac tamponade resulting from uninterrupted novel oral anticoagulants and uninterrupted warfarin during perioperative period of catheter ablation of atrial fibrillation: A meta-analysis [J]. Clinical Focus, 2022, 37(9): 773-778.
[13]	Wang Huixin, Zhao Fangqing, Zhang Xinyan, Hou Xiaowen. Relationship between uric acid and prognosis of Chinese patients with acute ischemic stroke: A meta analysis [J]. Clinical Focus, 2022, 37(9): 785-790.
[14]	Li Heng, Li Yonghui, Sun Xiaoqiang, Wang Lin, He Feng. Efficacy and safety of anticoagulant therapy for patients with heart failure in sinus rhythm [J]. Clinical Focus, 2022, 37(5): 406-411.
[15]	Li Jianqin, Sheng Yueyue, Zhou Yinmin, Shi Weiqing, Yang Xingchen. Safety of clopidogrel combined with statins on acute coronary syndrome in patients based on metabolic pathways by different cytochrome P450 enzyme: a Meta analysis [J]. Clinical Focus, 2022, 37(2): 101-105.

Advances in anticoagulant therapy after acute coronary syndrome

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments