Clinical Focus ›› 2025, Vol. 40 ›› Issue (5): 394-399.doi: 10.3969/j.issn.1004-583X.2025.05.002

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Meta-analysis of postoperative complications of self-expanding valve and balloon-expanding valve in transcatheter aortic valve replacement for severe aortic stenosis

Wen Can, Peng Yong, Liu Dan, Fan Jianfeng()   

  1. Second Department of Cardiology, the First Hospital of Nanchang, Nanchang 330000, China
  • Received:2025-02-14 Online:2025-05-20 Published:2025-05-23
  • Contact: Fan Jianfeng E-mail:390696271@qq.com

Abstract:

Objective To compare the postoperative complications of self-expanding valve (SEV) versus balloon-expanding valve (BEV) in transcatheter aortic valve replacement. Methods Articles reporting the advantages and disadvantages concerning the postoperative complications of SEV versus BEV in TAVR were searched in the English-language databases, such as PubMed and Cochrance, and Chinese-language databases, such as China National Knowledge Infrastructure (CNKI), Wanfang and VIP. Results A total of 9 articles, involving 5, 939 patients were included. There was a significant difference in the postoperative all-cause mortality between the SEV and BEV groups (risk ratio [RR]: 1.34, 95% confidence interval [CI]: 1.08, 1.66). SEV outperformed BEV in the postoperative mortality. There were no significant differences in the incidence postoperative stroke, proportion of pacemaker implantation, and the incidence of moderate-to-severe perivalvular leak between the SEV and BEV groups (P>0.05). Conclusion SEV is superior to BEV in all-cause mortality, but comparable in postoperative stroke, moderate-to-severe perivalvular leakage, pacemaker implantation and other postoperative complications.

Key words: transcatheter aortic valve replacement, self-expanding valves, balloon-expandable valves, complications

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