Abstract: ObjectiveTo investigate the factors on the prognosis of patients with HuntHess ⅣⅤ grade aneurismal subarachnoid hemorrhage.MethodsClinic characteristics， inflammation markers in blood and cerebrospinal fluid were investigated in 49 patients with HuntHess ⅣⅤ grade aneurismal subarachnoid hemorrhage; logistic regression was used for screening the factors  influencing the prognosis. ResultsThe treatment schemes， surgery time， Fisher classifications and postoperative complications were possibly associated with clinical outcomes (P＜0.05）; patients with different clinical outcomes had significantly different leucocytes on 1 d， 3 d and 7 d after admission(P＜0.05）; patients with different clinical outcomes had significantly different levels of CRP， but not with time; patients with different clinical outcomes had significantly different total protein and IgG in the cerebrospinal fluid (P＜0.05）; logistic regression showed that the factors influencing the prognosis were leucocytes on the seventh day， IgG in the cerebrospinal fluid and CRP on the third day， treatment scheme， Fisher classification and postoperative complication (P＜0.05）.ConclusionInflammation was possibly associated with the prognosis of patients with HuntHess ⅣⅤ grade aneurismal subarachnoid hemorrhage， treatment scheme， Fisher classification， and postoperative complication.

Key words: subarachnoid , hemorrhage, aneurysm, leukocytes, Creactive protein