Pathogenesis in alcoholic liver disease

doi:10.3969/j.issn.1004-583X.2016.07.007

Abstract

Abstract: Alcoholic liver disease (ALD) is a chronic disease caused by chronic alcohol abuse，and its histological spectrum ranges from hepatic steatosis， steatohepatitis， fibrosis， and ultimately to cirrhosis. Due to the incomplete understanding of pathogenesis， little progress has been made in ALD treatment. So， we attempt to discuss the effects of oxidative stress， endoplasmic reticulum stress，nitrative stress and lipid regulators in the pathogenesis of ALD.

Key words: hepatitis, alcoholic, oxidative stress, endoplasmic reticulum, cytokines

Li Yuanyuan， Hua Yanfang， Zhou Junying. Pathogenesis in alcoholic liver disease[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2016.07.007.

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URL: http://www.lchc.cn/EN/10.3969/j.issn.1004-583X.2016.07.007

http://www.lchc.cn/EN/Y2016/V31/I7/723

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Pathogenesis in alcoholic liver disease

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