Efficacy of  anti  tumor necrosis factor α  preparation  in achilles tendon enthesitis

doi:10.3969/j.issn.1004-583X.2018.05.017

Abstract

Abstract: Objective To explore the value of anti tumor necrosis factor α (TNFα) preparation in achilles tendon enthesitis in ankylosing spodylitis(AS) by ultrasonics. Methods We chose 32 AS patients who received anti TNFα preparation as experiment group and 29 AS patients who got conventional therapy as control group. The ultrasound images, erythrocyte sedimentation rate(ESR) and C reactive protein(CRP) were compared after six weeks of treatment between two groups. Results Compared with the control group, the ultrasound scores and clinic scores of achilles tendon enthesitis in experiment group witnessed significant reduction（both P<0.01). The changes of ESR and CRP in experiment group were more significant than those in control group(both P<0.01). Conclusion Anti TNFα preparation can improve the achilles tendon enthesitis in AS patients, which has been proved by ultrasonics.

Key words: spondylitis ankylosing, achilles tendon, ultrasonography, tumor neerosis factoralpha

Xie Jianli, Chen Haiying, Wang Junxiang, Zhang Ying, Xu Jinrong. Efficacy of anti tumor necrosis factor α preparation in achilles tendon enthesitis[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2018.05.017.

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URL: http://www.lchc.cn/EN/10.3969/j.issn.1004-583X.2018.05.017

http://www.lchc.cn/EN/Y2018/V33/I5/431

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Efficacy of anti tumor necrosis factor α preparation in achilles tendon enthesitis

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