Clinical Focus ›› 2025, Vol. 40 ›› Issue (8): 721-725.doi: 10.3969/j.issn.1004-583X.2025.08.009

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Pulmonary tuberculosis with the “crawling sign” as the main imaging feature:A case report and literature review

Li Guo1, Guo Sanjun2()   

  1. 1. Department of Respiratory and Critical Care Medicine, Xichong County People's Hospital, Nanchong 637200, China
    2. Department of Pathology, Sichuan Provincial Women's and Children's Hospital,Chengdu 610045, China
  • Received:2025-07-07 Online:2025-08-20 Published:2025-09-05
  • Contact: Guo Sanjun E-mail:991715017@qq.com

Abstract:

Objective To explore the imaging characteristics and clinical diagnostic value of pulmonary tuberculosis with the “crawling sign” as the main radiological feature. Methods Clinical and imaging data of a patient treated in the Respiratory Department of Xichong County People's Hospital were retrospectively analyzed. Results A 55-year-old man with type 2 diabetes mellitus presented with a pulmonary nodule found on routine examination 10 months earlier. During an 8-month follow-up, chest CT showed disease progression from a solitary nodule in the apicoposterior segment of the left upper lobe to a tubular lesion extending along the bronchovascular bundles toward the hilum, which was known as the crawling sign. Pathologic biopsy revealed granulomatous inflammation with necrosis. Tuberculosis (TB)-DNA testing confirmed a diagnosis of secondary pulmonary tuberculosis. Conclusion The crawling sign may serve as a suggestive imaging feature of pulmonary tuberculosis, particularly secondary pulmonary tuberculosis. It helps improve the accuracy of early diagnosis.

Key words: tuberculosis, pulmonary, crawling sign, imaging, granuloma

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