甘油三酯-葡萄糖指数与阻塞性睡眠呼吸暂停综合征相关性的研究进展
收稿日期: 2024-06-08
网络出版日期: 2024-09-24
甘油三酯-葡萄糖(triglyceride glucose,TyG)指数可反映胰岛素抵抗。阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea syndrome, OSAS)是以睡眠打鼾伴呼吸暂停和日间思睡为主要临床表现的睡眠呼吸疾病,已被证明与许多心脑血管疾病以及代谢性疾病如胰岛素抵抗、2型糖尿病等有关。目前大部分研究证实胰岛素抵抗与OSAS具有相关性,但尚未明确TyG指数与OSAS的相关性。本文针对TyG指数与OSAS的相关性进行综述,旨在为临床提供参考。
关键词： 睡眠呼吸暂停, 阻塞性; 甘油三酯-葡萄糖指数; 非酒精性脂肪性肝病; 心脑血管疾病; 认知障碍
马苗苗 , 王义艳 , 温甜甜 , 马丽群 . 甘油三酯-葡萄糖指数与阻塞性睡眠呼吸暂停综合征相关性的研究进展[J]. 临床荟萃, 2024 , 39(9) : 851 -854 . DOI: 10.3969/j.issn.1004-583X.2024.09.017
| [1] | 中国医师协会睡眠医学专业委员会. 成人阻塞性睡眠呼吸暂停多学科诊疗指南[J]. 中华医学杂志, 2018, 98(24):1902-1914. |
| [2] | Bikov A, Frent SM, Meszaros M, et al. Triglyceride-glucose index in non-diabetic, non-obese patients with obstructive sleep apnoea[J]. J Clin Med, 2021, 10(9):1932. |
| [3] | 赵建勇, 郭春月, 宋翠. 中老年人群甘油三酯葡萄糖乘积指数与高血压的关联研究[J]. 中国动脉硬化杂志, 2024, 32(7):583-589. |
| [4] | Li J, Dong Z, Wu H, et al. The triglyceride-glucose index is associated with atherosclerosis in patients with symptomatic coronary artery disease, regardless of diabetes mellitus and hyperlipidaemia[J]. Cardiovasc Diabetol, 2023, 22(1):224. |
| [5] | Yang Y, Huang X, Wang Y, et al. The impact of triglyceride-glucose index on ischemic stroke: A systematic review and meta-analysis[J]. Cardiovasc Diabetol, 2023, 22(1):2. |
| [6] | Yu H, Tao L, Li YG, et al. Association between triglyceride-glucose index trajectories and carotid atherosclerosis progression[J]. Cardiovasc Diabetol, 2023, 22(1):130. |
| [7] | Yeghiazarians Y, Jneid H, Tietjens JR, et al. Obstructive sleep apnea and cardiovascular disease: A scientific statement from the American Heart Association[J]. Circulation, 2021, 144(3):e56-e67. |
| [8] | 张勇, 蔡翔, 钟钟, 等. 甘油三酯葡萄糖乘积指数对急性冠状动脉综合征患者行急诊PCI术远期预后的预测价值[J]. 中国动脉硬化杂志, 2023, 31(8):687-696. |
| [9] | 张永红, 陈林慧, 刘强, 等. 2型糖尿病合并睡眠呼吸暂停低通气综合征患者氧化应激对血糖波动影响的研究[J]. 中国糖尿病杂志, 2024, 32(7):515-518. |
| [10] | Kang HH, Kim SW, Lee SH. Association between triglyceride glucose index and obstructive sleep apnea risk in Korean adults: A cross-sectional cohort study[J]. Lipids Health Dis, 2020, 19(1):182. |
| [11] | S?kücü SN, Ayd?n ?, Sat?c? C, et al. Triglyceride-glucose index as a predictor of obstructive sleep apnoea severity in the absence of traditional risk factors[J]. Arq Neuropsiquiatr, 2023, 81(10):891-897. |
| [12] | 陈琳, 欧阳若芸, 杨悦, 等. 阻塞性睡眠呼吸暂停与甘油三酯葡萄糖指数的相关性[J]. 中国现代医学杂志, 2023, 33(12):65-71. |
| [13] | Wang C, Shi M, Lin C, et al. Association between the triglyceride glucose index and obstructive sleep apnea and its symptoms: Results from the NHANES[J]. Lipids Health Dis, 2024, 23(1):133. |
| [14] | Huang J, Zhuang J, Zheng H, et al. A machine learning prediction model of adult obstructive sleep apnea based on systematically evaluated common clinical biochemical indicators[J]. Nat Sci Sleep, 2024, 16:413-428. |
| [15] | Behnoush AH, Khalaji A, Ghondaghsaz E, et al. Triglyceride-glucose index and obstructive sleep apnea: A systematic review and meta-analysis[J]. Lipids Health Dis, 2024, 23(1):4. |
| [16] | Meng X, Wen H, Lian L. Association between triglyceride glucose-body mass index and obstructive sleep apnea: A study from NHANES 2015-2018[J]. Front Nutr, 2024, 11:1424881. |
| [17] | Pan Q, Li H, Gan X, et al. Relationship between slow-wave sleep and serum γ-glutamine transaminase in non-obese men with obstructive sleep apnea-hypopnea syndrome[J]. Sleep Breath, 2023, 27(5):1717-1724. |
| [18] | Meszaros M, Kunos L, Tarnoki AD, et al. The role of soluble low-density lipoprotein receptor-related protein-1 in obstructive sleep apnoea[J]. J Clin Med, 2021, 10(7):1494. |
| [19] | 潘启源, 李瀚卿, 甘谢雨, 等. 非肥胖女性OSAHS患者慢波睡眠与TyG指数的相关性研究[J]. 重庆医学, 2023, 52(18):2834-2838. |
| [20] | Zou J, Wang Y, Xu H, et al. The use of visceral adiposity variables in the prediction of obstructive sleep apnea: Evidence from a large cross-sectional study[J]. Sleep Breath, 2020, 24(4):1373-1382. |
| [21] | Adeva-Andany MM, Domínguez-Montero A, Castro-Quintela E, et al. Hypoxia-induced insulin resistance mediates the elevated cardiovascular risk in patients with obstructive sleep apnea: A comprehensive review[J]. Rev Cardiovasc Med, 2024, 25(6):231. |
| [22] | 蒋绒, 李永霞. 甘油三酯葡萄糖乘积指数联合肥胖指标对阻塞性睡眠呼吸暂停患者发生非酒精性脂肪性肝病的预测价值[J]. 临床肝胆病杂志, 2023, 39(3):546-551. |
| [23] | Cai Y, Chen J, Deng X, et al. Triglyceride-glucose index and combined indicators: Effective indicators for screening NAFLD in snoring patients[J]. BMC Pulm Med, 2024, 24(1):359. |
| [24] | 宋松松, 时小凤, 童嘉毅, 等. 甘油三酯葡萄糖指数与阻塞性睡眠呼吸暂停患者肱踝脉搏波速度的相关性[J]. 中国临床研究, 2024, 37(1):70-74. |
| [25] | 李翔, 牟涛, 李益飞, 等. 阻塞性睡眠呼吸暂停与缺血性卒中患者甘油三酯葡萄糖指数的相关性[J]. 国际脑血管病杂志, 2022, 30(3):184-189. |
| [26] | Ding L, Jiang X. The mediating effect of TyG and its derived indices in the association between OSAHS and atherosclerosis in patients with T2DM[J]. Sleep Breath, 2024. |
| [27] | Hu J, Cai X, Li N, et al. Association between triglyceride glucose index-waist circumference and risk of first myocardial infarction in Chinese hypertensive patients with obstructive sleep apnoea: An observational cohort study[J]. Nat Sci Sleep, 2022, 14:969-980. |
| [28] | Zhou T, Wang Y, Xu Y, et al. Multimodal data integration for enhanced longitudinal prediction for cardiac and cerebrovascular events following initial diagnosis of obstructive sleep apnea syndrome[J]. J Glob Health, 2024, 14:04103. |
| [29] | Pan Q, Li H, Gan X, et al. Correlation between cognitive impairment and serum markers in patients with obstructive sleep apnea-hypopnea syndrome[J]. Sleep Breath, 2024, 28(2):683-690. |
| [30] | 侯丁淳, 魏玥, 孙玉梅, 等. 中国中老年人群甘油三酯葡萄糖指数-腰围身高比与认知障碍关联的队列研究[J]. 中华流行病学杂志, 2024, 45(6):802-808. |
| [31] | Wu Y, Yang Y, Zhang J, et al. The change of triglyceride-glucose index may predict incidence of stroke in the general population over 45 years old[J]. Cardiovasc Diabetol, 2023, 22(1):132. |
/
| 〈 |
|
〉 |