功能磁共振与多模态影像整合在阿尔茨海默病早期诊断中的研究进展

doi:10.3969/j.issn.1004-583X.2026.02.015

摘要/Abstract

摘要：

阿尔茨海默病(Alzheimer’s disease,AD)作为最常见的神经退行性疾病,其早期诊断与病理机制研究依赖于神经影像学技术的发展。本文重点围绕功能磁共振成像与多模态影像整合应用展开,从脑结构影像学改变、脑功能网络异常、动态功能连接分析以及多模态影像融合等方面,总结了AD早期影像学研究的主要发现。重点阐述了功能磁共振成像在默认模式网络功能异常及其动态时空特征建模中的关键作用,以及多模态影像整合在提升AD早期诊断准确性和疾病分期中的优势。同时分析当前研究面临的挑战,展望未来基于深度学习与标准化生物标志物的发展方向,为AD的早期诊断与精准干预提供影像学视角的全面参考。

中图分类号:

R745.7

付玉婷, 赵捷, 李光昊, 黄欢. 功能磁共振与多模态影像整合在阿尔茨海默病早期诊断中的研究进展[J]. 临床荟萃, 2026, 41(2): 183-187.

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https://www.lchc.cn/CN/Y2026/V41/I2/183

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功能磁共振与多模态影像整合在阿尔茨海默病早期诊断中的研究进展

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