缺血性卒中急性期的抗血小板治疗

doi:10.3969/j.issn.1004-583X.2026.06.001

摘要/Abstract

摘要：

缺血性卒中急性期是神经功能恶化与早期复发的高危阶段。抗血小板治疗的核心在于尽早抑制血小板活化,在降低缺血事件风险的同时严格控制出血并发症。对于非心源性急性缺血性卒中患者,应在排除脑出血的前提下尽早启动抗血小板治疗,以降低卒中早期进展、复发以及其他血管事件风险。本文系统梳理了近30年来急性期抗血小板治疗的发展历程以及最新研究进展,以期为临床实践中抗血小板药物的精准选择与个体化治疗策略的制定提供理论依据和参考。

关键词: 缺血性卒中, 急性期, 抗血小板治疗

Abstract:

The acute phase of ischemic stroke is a high-risk period for neurological deterioration and early recurrence. The primary goal of antiplatelet therapy is to inhibit platelet activation as early as possible, thereby reducing the risk of ischemic events while strictly controlling bleeding complications. In patients with non-cardioembolic acute ischemic stroke, antiplatelet therapy should be initiated as early as possible after intracranial hemorrhage has been excluded, in order to reduce the risks of early stroke progression, recurrence, and other vascular events. This article systematically reviews the development of acute-phase antiplatelet therapy over the past 30 years and the latest research advances, with the aim of providing a theoretical basis and reference for the precise selection of antiplatelet agents and the development of individualized treatment strategies in clinical practice.

Key words: ischemic stroke, acute phase, antiplatelet therapy

中图分类号:

R743.3

欧阳芊, 赵颖, 孟珩, 徐安定. 缺血性卒中急性期的抗血小板治疗[J]. 临床荟萃, 2026, 41(6): 485-492.

Ouyang Qian, Zhao Ying, Meng Heng, Xu Anding. Antiplatelet therapy in the acute phase of ischemic stroke[J]. Clinical Focus, 2026, 41(6): 485-492.

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链接本文: https://www.lchc.cn/CN/10.3969/j.issn.1004-583X.2026.06.001

https://www.lchc.cn/CN/Y2026/V41/I6/485

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