肾结核的多模态融合诊断

doi:10.3969/j.issn.1004-583X.2025.08.016

摘要/Abstract

摘要：

肾结核是一种严重的泌尿系统感染性疾病,早期诊断对保护肾功能及改善预后至关重要。由于肾结核起病隐匿、发病过程缓慢、临床症状不典型,是一种潜伏性极强的疾病,诊断难度大,容易造成误诊。目前,肾结核主要依赖临床表现、实验室检查和影像学检查等手段综合诊断。近年来,利福平耐药实时荧光定量核酸扩增检测技术、环介导等温扩增技术等多种分子生物学技术著提升了病原学检测效率;影像学技术与人工智能的结合实现了对病变的更精准的定位与定量分析;脂阿拉伯甘露聚糖、血清甲壳质酶蛋白40等新型生物标志物为无创诊断提供了新方向。本文系统综述肾结核诊断技术的现状与前沿进展,探讨多模态联合诊断策略的临床价值,以期减少肾结核临床误诊漏诊,为优化其诊断路径提供理论依据。

关键词: 肾结核, 多模态, 分子生物学诊断, 影像组学, 人工智能

中图分类号:

R527.1

李逍山, 尚攀峰. 肾结核的多模态融合诊断[J]. 临床荟萃, 2025, 40(8): 758-763.

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链接本文: https://www.lchc.cn/CN/10.3969/j.issn.1004-583X.2025.08.016

https://www.lchc.cn/CN/Y2025/V40/I8/758

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肾结核的多模态融合诊断

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