关键词: 急性肾损伤, 少尿, 透析

Abstract: Objective  To investigate the etiology， clinical features and prognosis of acute renal injury(AKI). Methods  The clinical characteristics of 86 patients with AKI  were analyzed retrospectively.They were divided into the recovery group (including renal function recovered completely and partially restored) and the nonrecovery group (including death， automatic discharge and longterm dialysis).  The age， gender， hemoglobin， serum albumin， serum uric acid， basic diseases (hypertension， diabetes， coronary heart disease)， dialysis rate and rate of oliguria were statistically analyzed.  Additionally，the risk factors of poor prognosis were analyzed. Results  Of  86 patients， 4 patients died (4.65%)， 13 patients were discharged automatically (15.12%)， 2 patients received longterm dialysis(2.33%)， and 67 patients improved (77.90%)， the main causes of the disease included insufficient anterior renal perfusion， infection， postrenal obstruction， cardiac insufficiency， drugs and so on， among which renal insufficiency and infection were the main causes. There were no significant differences in age， gender， hemoglobin， serum albumin， basic disease， dialysis rate between two groups (P>0.05). The blood uric acid level and oliguria incidence in nonrecovery group were significantly higher than those in the recovery group (P<0.05). Multiple logistic regression analysis showed that oliguria was an independent risk factor for poor prognosis in patients with AKI. Conclusion  AKI patients have high clinical morbidity and mortality， early diagnosis and active intervention can improve the clinical prognosis; prerenal hypoperfusion and infection; oliguria is an independent risk factor of poor prognosis of patients with AKI.

Key words: acute kidney injury, oliguria, dialysis