临床荟萃 ›› 2025, Vol. 40 ›› Issue (10): 918-922.doi: 10.3969/j.issn.1004-583X.2025.10.007

• 论著 • 上一篇    下一篇

机械切除与高频电切除6~15 mm无蒂结直肠息肉的临床效果

刘东亚, 孙正路, 杜莹莹, 韩大正()   

  1. 河南大学第一附属医院 消化内科, 河南 开封 475000
  • 收稿日期:2025-07-01 出版日期:2025-10-20 发布日期:2025-10-31
  • 通讯作者: 韩大正 E-mail:13569519096@163.com
  • 基金资助:
    2023年度河南省医学科技攻关计划联合共建项目——结直肠息肉机械切除与高频电切除临床应用研究分析(LHGJ20230422)

Clinical efficacy of mechanical resection versus high-frequency electrical resection of 6-15 mm sessile colorectal polyps

Liu Dongya, Sun Zhenglu, Du Yingying, Han Dazheng()   

  1. Department of Gastroenterology, the First Affiliated Hospital of Henan University, Kaifeng 475000, China
  • Received:2025-07-01 Online:2025-10-20 Published:2025-10-31
  • Contact: Han Dazheng E-mail:13569519096@163.com

摘要:

目的 探讨机械切除与高频电切除在6~15 mm无蒂结直肠息肉患者中的临床效果。方法 选取2023年1月-2024年12月河南大学第一附属医院收治的6~15 mm无蒂结直肠息肉患者120例,采用随机数字表法分为机械切除组(采用冷圈套法)和高频电切组(采用热圈套法)进行切除,每组各60例。对比两组手术治疗效果、围术期指标、血清胃肠道功能指标以及并发症发生率。结果 机械切除组回盲部插管占比高于高频电切除组,黏膜下层累积损伤占比低于高频电切除组(P<0.05),两组息肉回收占比、息肉整块切除占比、全切切除率差异无统计学意义(P>0.05)。机械切除组手术时间、术后首次排气时间、住院时长、术后首次排便时间、术中出血量均低于高频电切除组(P<0.05)。两组术前胃肠道功能指标差异无统计学意义(P>0.05);术后3 d,机械切除组肠道脂肪酸结合蛋白、血管活性肠肽、二胺氧化酶水平均低于高频电切除组(P<0.05)。机械切除组并发症发生率低于高频电切除组(P<0.05)。结论 机械切除(采用冷圈套法)和高频电切(采用热圈套法)切除6~15 mm无蒂结直肠息肉均能取得较好的治疗效果,但是机械切除的整体效果优于高频电切,对于6~15 mm无蒂结直肠息肉患者,可首选机械切除手术治疗。

关键词: 肠息肉, 机械切除, 高频电切除, 临床效果

Abstract:

Objective To compare the clinical effects of mechanical resection and high-frequency electrocautery resection in patients with 6-15 mm sessile colorectal polyps. Methods A total of 120 patients with 6-15 mm sessile colorectal polyps treated at our hospital from January 2023 to December 2024 were randomly assigned (random number table) to either a mechanical resection group using the cold snare technique or a high-frequency electrocautery resection group using the hot snare technique (n=60 each). Surgical outcomes, perioperative recovery metrics, serum gastrointestinal function markers, and complication rates were compared between groups. Results The mechanical resection group achieved a significantly higher cecal intubation rate and a significantly lower proportion of cumulative submucosal injury than the high-frequency electrocautery group (both P<0.05). The proportions of polyp recovery and polyp en bloc resection, and the total resection rate were comparable between the two groups ( all P>0.05).Operative time, time to first postoperative flatus, length of hospital stay, time to first postoperative bowel movement, and intraoperative blood loss were significantly lower in the mechanical resection group (all P<0.05). There was no significant difference in preoperative gastrointestinal function between groups (P>0.05). At postoperative day 3, serum levels of intestinal fatty acid-binding protein (I-FABP), vasoactive intestinal peptide (VIP), and diamine oxidase (DAO) were significantly lower in the mechanical resection group than in the high-frequency electrocautery group (all P<0.05). The overall incidence of complications was significantly lower with mechanical resection (P<0.05). Conclusion Both mechanical resection (cold snare) and high-frequency electrocautery resection (hot snare) provide effective treatment for 6-15 mm sessile colorectal polyps. However, mechanical resection demonstrates overall superiority in procedural performance, tissue safety, recovery, and complication profile, and may be recommended as the first-line technique for this population.

Key words: rectal polyp, mechanical cold snare polypectomy, high-frequency electrosurgical hot snare polypectomy, clinical effects

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