IgA血管炎肾炎影响因素及生物标志物的研究进展

doi:10.3969/j.issn.1004-583X.2026.05.013

摘要/Abstract

摘要：

IgA血管炎肾炎(immunoglobulin A vasculitis nephritis,IgAVN)是IgA血管炎累及肾脏所导致的继发性肾脏疾病,远期有进展为慢性肾脏病和终末期肾病的风险。该病目前发病机制尚不完全明确,患者的临床情况与肾脏病理改变各不相同,对治疗的反应也存在差异,预后情况相差较大。指南指出,IgAVN的诊断金标准仍是肾脏穿刺活检术,但肾脏穿刺活检术并不能被所有患者接受,这极大地影响了疾病的临床应用。因此,深入探究IgAVN发生与进展的相关因素,能为该疾病的预防和干预提供参考依据,本文通过对国内外公开发表的相关研究进行综述,系统回顾IgAVN的影响因素,并重点聚焦于相关的血清和尿液生物标志物,以期为临床更好地预防疾病的发生和延缓疾病的进展提供新的思路和治疗策略。

关键词: IgA血管炎肾炎, 影响因素, 预后, 生物标志物

中图分类号:

R692.3

翟琳清, 张浩, 姚灿, 孟雪. IgA血管炎肾炎影响因素及生物标志物的研究进展[J]. 临床荟萃, 2026, 41(5): 468-474.

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链接本文: https://www.lchc.cn/CN/10.3969/j.issn.1004-583X.2026.05.013

https://www.lchc.cn/CN/Y2026/V41/I5/468

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IgA血管炎肾炎影响因素及生物标志物的研究进展

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